According to a study, deep brain stimulation (DBS) can serve as a potential therapy for treatment-resistant depression. The study found DBS to the medial forebrain bundle, which is linked to reward and motivation, revealed metabolic brain changes over 12 months.
The Molecular Psychiatry study found that “metabolic changes lay along cortico-limbic nodes structurally connected to the DBS target site. Such observed metabolic changes following DBS correlated with clinical response provide insights into how future studies can elaborate such data to create biomarkers to predict
